Ontology highlight
ABSTRACT:
SUBMITTER: Balsalobre L
PROVIDER: S-EPMC161831 | biostudies-literature | 2003 Jul
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20030701 7
A total of 46 ciprofloxacin-resistant (Cip(r)) Streptococcus pneumoniae strains were isolated from 1991 to 2001 at the Hospital of Bellvitge. Five of these strains showed unexpectedly high rates of nucleotide variations in the quinolone resistance-determining regions (QRDRs) of their parC, parE, and gyrA genes. The nucleotide sequence of the full-length parC, parE, and gyrA genes of one of these isolates revealed a mosaic structure compatible with an interspecific recombination origin. Southern ...[more]