Functional role of aspartic proteinase cathepsin D in insect metamorphosis.
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ABSTRACT:
SUBMITTER: Gui ZZ
PROVIDER: S-EPMC1629011 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Publications
Functional role of aspartic proteinase cathepsin D in insect metamorphosis.
Gui Zhong Zheng ZZ Lee Kwang Sik KS Kim Bo Yeon BY Choi Yong Soo YS Wei Ya Dong YD Choo Young Moo YM Kang Pil Don PD Yoon Hyung Joo HJ Kim Iksoo I Je Yeon Ho YH Seo Sook Jae SJ Lee Sang Mong SM Guo Xijie X Sohn Hung Dae HD Jin Byung Rae BR
BMC developmental biology 20061025
<h4>Background</h4>Metamorphosis is a complex, highly conserved and strictly regulated development process that involves the programmed cell death of obsolete larval organs. Here we show a novel functional role for the aspartic proteinase cathepsin D during insect metamorphosis.<h4>Results</h4>Cathepsin D of the silkworm Bombyx mori (BmCatD) was ecdysone-induced, differentially and spatially expressed in the larval fat body of the final instar and in the larval gut of pupal stage, and its expres ...[more]
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