Ontology highlight
ABSTRACT:
SUBMITTER: Xiang Y
PROVIDER: S-EPMC1630414 | biostudies-literature | 2006 Nov
REPOSITORIES: biostudies-literature
Xiang Ye Y Morais Marc C MC Battisti Anthony J AJ Grimes Shelley S Jardine Paul J PJ Anderson Dwight L DL Rossmann Michael G MG
The EMBO journal 20061019 21
Cryo-electron microscopy three-dimensional reconstructions have been made of mature and of emptied bacteriophage phi29 particles without making symmetry assumptions. Comparisons of these structures with each other and with the phi29 prohead indicate how conformational changes might initiate successive steps of assembly and infection. The 12 adsorption capable 'appendages' were found to have a structure homologous to the bacteriophage P22 tailspikes. Two of the appendages are extended radially ou ...[more]