Ontology highlight
ABSTRACT:
SUBMITTER: Senger K
PROVIDER: S-EPMC1635109 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Senger Kate K Harris Kristina K Levine Mike M
Proceedings of the National Academy of Sciences of the United States of America 20061010 43
Drosophila responds to infection by producing a broad range of antimicrobial agents in the fat body and more restricted responses in tissues such as the gut, trachea, and malpighian tubules. The regulation of antimicrobial genes in larval fat depends on linked Rel/NF-kappaB and GATA binding sites. Serpent functions as the major GATA transcription factor in the larval fat body. However, the transcriptional regulation of other tissue-specific responses is less well understood. Here, we present evi ...[more]