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Novel conserved assembly factor of the bacterial flagellum.


ABSTRACT: TP0658 (FliW) and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum; FliC in most other species). Mutants of orthologs in Bacillus subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin in a way similar to FliS, suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum.

SUBMITTER: Titz B 

PROVIDER: S-EPMC1636259 | biostudies-literature | 2006 Nov

REPOSITORIES: biostudies-literature

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Novel conserved assembly factor of the bacterial flagellum.

Titz Björn B   Rajagopala Seesandra V SV   Ester Claudia C   Häuser Roman R   Uetz Peter P  

Journal of bacteriology 20060825 21


TP0658 (FliW) and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum; FliC in most other species). Mutants of orthologs in Bacillus subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin in a way similar to FliS, suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum. ...[more]

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