Ontology highlight
ABSTRACT:
SUBMITTER: Ericsson TA
PROVIDER: S-EPMC164520 | biostudies-literature | 2003 May
REPOSITORIES: biostudies-literature
Ericsson Thomas A TA Takeuchi Yasuhiro Y Templin Christian C Quinn Gary G Farhadian Shelli F SF Wood James C JC Oldmixon Beth A BA Suling Kristen M KM Ishii Jennifer K JK Kitagawa Yoshinori Y Miyazawa Takayuki T Salomon Daniel R DR Weiss Robin A RA Patience Clive C
Proceedings of the National Academy of Sciences of the United States of America 20030509 11
Xenotransplantation of porcine tissues has the potential to treat a wide variety of major health problems including organ failure and diabetes. Balanced against the potential benefits of xenotransplantation, however, is the risk of human infection with a porcine microorganism. In particular, the transmission of porcine endogenous retrovirus (PERV) is a major concern [Chapman, L. E. & Bloom, E. T. (2001) J. Am. Med. Assoc. 285, 2304-2306]. Here we report the identification of two, sequence-relate ...[more]