Ontology highlight
ABSTRACT:
SUBMITTER: Tyedmers J
PROVIDER: S-EPMC16525 | biostudies-literature | 2000 Jun
REPOSITORIES: biostudies-literature
Tyedmers J J Lerner M M Bies C C Dudek J J Skowronek M H MH Haas I G IG Heim N N Nastainczyk W W Volkmer J J Zimmermann R R
Proceedings of the National Academy of Sciences of the United States of America 20000601 13
Cotranslational protein transport into dog pancreas microsomes involves the Sec61p complex plus a luminal heat shock protein 70. Posttranslational protein transport into the yeast endoplasmic reticulum (ER) involves the so-called Sec complex in the membrane, comprising a similar Sec61p subcomplex, the putative signal peptide receptor subcomplex, and the heat shock protein 40-type subunit, Sec63p, plus a luminal heat shock protein 70. Recently, human homologs of yeast proteins Sec62p and Sec63p w ...[more]