Mutational analysis of cell wall biosynthesis in Mycobacterium avium.
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ABSTRACT:
SUBMITTER: Laurent JP
PROVIDER: S-EPMC166487 | biostudies-literature | 2003 Aug
REPOSITORIES: biostudies-literature
Publications
Mutational analysis of cell wall biosynthesis in Mycobacterium avium.
Laurent Jean-Pierre JP Hauge Kirsten K Burnside Kellie K Cangelosi Gerard G
Journal of bacteriology 20030801 16
The cell wall of the environmental pathogen Mycobacterium avium is important to its virulence and intrinsic antimicrobial resistance. To identify genes involved in cell wall biosynthesis, "transposome" insertion libraries were screened for mutants with altered colony morphology on medium containing the lipoprotein stain Congo red. Nineteen such mutants were isolated and mapped, including 10 with insertions in a functional island of cell wall biosynthetic genes that spans approximately 40 kb of t ...[more]
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