Ontology highlight
ABSTRACT:
SUBMITTER: Sauter C
PROVIDER: S-EPMC167641 | biostudies-literature | 2003 Jul
REPOSITORIES: biostudies-literature
Sauter Claude C Basquin Jérôme J Suck Dietrich D
Nucleic acids research 20030701 14
The Hfq protein was discovered in Escherichia coli in the early seventies as a host factor for the Qbeta phage RNA replication. During the last decade, it was shown to be involved in many RNA processing events and remote sequence homology indicated a link to spliceosomal Sm proteins. We report the crystal structure of the E.coli Hfq protein showing that its monomer displays a characteristic Sm-fold and forms a homo-hexamer, in agreement with former biochemical data. Overall, the structure of the ...[more]