Unknown

Dataset Information

0

GeneFizz: A web tool to compare genetic (coding/non-coding) and physical (helix/coil) segmentations of DNA sequences. Gene discovery and evolutionary perspectives.


ABSTRACT: The GeneFizz (http://pbga.pasteur.fr/GeneFizz) web tool permits the direct comparison between two types of segmentations for DNA sequences (possibly annotated): the coding/non-coding segmentation associated with genomic annotations (simple genes or exons in split genes) and the physics-based structural segmentation between helix and coil domains (as provided by the classical helix-coil model). There appears to be a varying degree of coincidence for different genomes between the two types of segmentations, from almost perfect to non-relevant. Following these two extremes, GeneFizz can be used for two purposes: ab initio physics-based identification of new genes (as recently shown for Plasmodium falciparum) or the exploration of possible evolutionary signals revealed by the discrepancies observed between the two types of information.

SUBMITTER: Yeramian E 

PROVIDER: S-EPMC169033 | biostudies-literature | 2003 Jul

REPOSITORIES: biostudies-literature

altmetric image

Publications

GeneFizz: A web tool to compare genetic (coding/non-coding) and physical (helix/coil) segmentations of DNA sequences. Gene discovery and evolutionary perspectives.

Yeramian Edouard E   Jones Louis L  

Nucleic acids research 20030701 13


The GeneFizz (http://pbga.pasteur.fr/GeneFizz) web tool permits the direct comparison between two types of segmentations for DNA sequences (possibly annotated): the coding/non-coding segmentation associated with genomic annotations (simple genes or exons in split genes) and the physics-based structural segmentation between helix and coil domains (as provided by the classical helix-coil model). There appears to be a varying degree of coincidence for different genomes between the two types of segm  ...[more]

Similar Datasets

| S-EPMC2093931 | biostudies-literature
| S-EPMC4987877 | biostudies-literature
| S-EPMC1847453 | biostudies-literature
| S-EPMC1622844 | biostudies-literature
| S-EPMC7805433 | biostudies-literature
| S-EPMC7124434 | biostudies-literature
| S-EPMC4201159 | biostudies-literature
| S-EPMC8279765 | biostudies-literature
| S-EPMC2562949 | biostudies-literature
| S-EPMC1636073 | biostudies-literature