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Molecular characterization of Cryptosporidium spp. from children in Kolkata, India.


ABSTRACT: The intracellular parasite Cryptosporidium is responsible for severe diarrhea in immunocompromised persons in developing countries. Few studies on the characterization of the parasite in India are available. In this study, molecular characterization of the parasite from diarrheic children was carried out by PCR-restriction fragment length polymorphism analysis. At least three genotypes were identified. Out of 40 positive samples, 35 were positive for C. hominis, 4 were positive for C. parvum, and 1 was positive for C. felis. This study clearly suggests that cryptosporidiosis in this region is caused largely by anthroponotic transmission.

SUBMITTER: Das P 

PROVIDER: S-EPMC1698361 | biostudies-literature | 2006 Nov

REPOSITORIES: biostudies-literature

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Molecular characterization of Cryptosporidium spp. from children in Kolkata, India.

Das Pradeep P   Roy Seuli Saha SS   MitraDhar Kakali K   Dutta Phalguni P   Bhattacharya Mihir K MK   Sen Abhik A   Ganguly Sandipan S   Bhattacharya Sujit K SK   Lal Altaf A AA   Xiao Lihua L  

Journal of clinical microbiology 20060913 11


The intracellular parasite Cryptosporidium is responsible for severe diarrhea in immunocompromised persons in developing countries. Few studies on the characterization of the parasite in India are available. In this study, molecular characterization of the parasite from diarrheic children was carried out by PCR-restriction fragment length polymorphism analysis. At least three genotypes were identified. Out of 40 positive samples, 35 were positive for C. hominis, 4 were positive for C. parvum, an  ...[more]

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