Ontology highlight
ABSTRACT:
SUBMITTER: Cahill S
PROVIDER: S-EPMC1713250 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Cahill Susanne S Smyth Paul P Finn Stephen P SP Denning Karen K Flavin Richard R O'Regan Esther M EM Li Jinghuan J Potratz Astrid A Guenther Simone M SM Henfrey Richard R O'Leary John J JJ Sheils Orla O
Molecular cancer 20061211
<h4>Background</h4>microRNAs (miRNAs) are a group of non-coding single stranded RNAs measuring approximately 22 nt in length that have been found to control cell growth, differentiation and apoptosis. miRNAs negatively regulate their target genes and recently have been implicated in tumourigenesis. Furthermore, miRNA expression profiling correlates with various cancers, with these genes thought to act as both tumour suppressors and oncogenes. ret/PTC 1 is an oncogene with constitutive kinase act ...[more]