Ontology highlight
ABSTRACT:
SUBMITTER: Evans DG
PROVIDER: S-EPMC1735122 | biostudies-literature | 2002 May
REPOSITORIES: biostudies-literature
Evans D G R DG Baser M E ME McGaughran J J Sharif S S Howard E E Moran A A
Journal of medical genetics 20020501 5
<h4>Background</h4>Cross sectional studies have shown that 1-2% of patients with neurofibromatosis 1 (NF1) develop malignant peripheral nerve sheath tumours (MPNST). However, no population based longitudinal studies have assessed lifetime risk.<h4>Methods</h4>NF1 patients with MPNST were ascertained from two sources for our north west England population of 4.1 million in the 13 year period 1984-1996: the North West Regional NF1 Register and review of notes of patients with MPNST in the North Wes ...[more]