Ontology highlight
ABSTRACT:
SUBMITTER: Joo JM
PROVIDER: S-EPMC1762102 | biostudies-literature | 2006 Nov
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20061101 46
A rhodium(I)-catalyzed tandem cyclization of alkynes has been developed. The reaction allows for multiple bond formations to occur at both the alpha- and beta-positions of alkynes under mild conditions to yield a variety of fused ring systems as the products. In the presence of triethylamine and the complex derived from [Rh(COD)Cl]2 and P(4-F-C6H4)3, a terminal alkyne is converted to a rhodium alkynyl species which reacts with a tethered alkyl halide at the beta-position to provide a beta,beta-d ...[more]