The PKA-CREB system encoded by the honeybee genome.
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ABSTRACT:
SUBMITTER: Eisenhardt D
PROVIDER: S-EPMC1769443 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Publications
The PKA-CREB system encoded by the honeybee genome.
Eisenhardt D D Kühn C C Leboulle G G
Insect molecular biology 20061001 5
The cAMP-dependent kinase (PKA) plays a crucial part in long-term memory formation in the honeybee (Apis mellifera). One of the putative substrates of the PKA activity is the cAMP response element binding protein (CREB), a transcription factor in the bZIP protein family. We searched the honeybee genome to characterize genes from the CREB/CREM and the PKA families. We identified two genes that encode regulatory subunits and three genes encode catalytic subunits of PKA. Eight genes code for bZIP p ...[more]
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