Ontology highlight
ABSTRACT:
SUBMITTER: Watson CS
PROVIDER: S-EPMC1769494 | biostudies-literature | 2006 Dec
REPOSITORIES: biostudies-literature
Journal of molecular signaling 20061205
<h4>Background</h4>The effects of estrogens on dopamine (DA) transport may have important implications for the increased incidence of neurological disorders in women during life stages when hormonal fluctuations are prevalent, e.g. during menarche, reproductive cycling, pregnancy, and peri-menopause.<h4>Results</h4>The activity of the DA transporter (DAT) was measured by the specific uptake of 3H-DA. We found that low concentrations (10(-14) to 10(-8) M) of 17beta-estradiol (E2) inhibit uptake v ...[more]