Ontology highlight
ABSTRACT:
SUBMITTER: Luo JH
PROVIDER: S-EPMC1769554 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Luo Jian-Hua JH Ren Baoguo B Keryanov Sergei S Tseng George C GC Rao Uma N M UN Monga Satdarshan P SP Strom Steven S Demetris Anthony J AJ Nalesnik Michael M Yu Yan P YP Ranganathan Sarangarajan S Michalopoulos George K GK
Hepatology (Baltimore, Md.) 20061001 4
This study analyzed gene expression patterns and global genomic alterations in hepatocellular carcinomas (HCC), hepatoblastomas (HPBL), tissue adjacent to HCC and normal liver tissue derived from normal livers and hepatic resections. We found that HCC and adjacent non-neoplastic cirrhotic tissue have considerable overlap in gene expression patterns compared to normal liver. Several genes including Glypican 3, spondin-2, PEG10, EDIL3 and Osteopontin are over-expressed in HCC vs. adjacent tissue w ...[more]