A chimeric prokaryotic ancestry of mitochondria and primitive eukaryotes.
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ABSTRACT:
SUBMITTER: Karlin S
PROVIDER: S-EPMC17755 | biostudies-literature | 1999 Aug
REPOSITORIES: biostudies-literature
Publications
A chimeric prokaryotic ancestry of mitochondria and primitive eukaryotes.
Karlin S S Brocchieri L L Mrázek J J Campbell A M AM Spormann A M AM
Proceedings of the National Academy of Sciences of the United States of America 19990801 16
We provide data and analysis to support the hypothesis that the ancestor of animal mitochondria (Mt) and many primitive amitochondrial (a-Mt) eukaryotes was a fusion microbe composed of a Clostridium-like eubacterium and a Sulfolobus-like archaebacterium. The analysis is based on several observations: (i) The genome signatures (dinucleotide relative abundance values) of Clostridium and Sulfolobus are compatible (sufficiently similar) and each has significantly more similarity in genome signature ...[more]
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