Ontology highlight
ABSTRACT:
SUBMITTER: Fife MS
PROVIDER: S-EPMC1779449 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Fife Mark S MS Gutierrez Ana A Ogilvie Emma M EM Stock Carmel J W CJ Samuel Jane M JM Thomson Wendy W Mack Lisa F LF Lewis Cathryn M CM Woo Patricia P
Arthritis research & therapy 20060101 5
Juvenile idiopathic arthritis (JIA) is the most common cause of chronic childhood disability and encompasses a number of disease subgroups. In this study we have focused on systemic JIA (sJIA), which accounts for approximately 11% of UK JIA cases. This study reports the investigation of three members of the IL10 gene family as candidate susceptibility loci in children with sJIA. DNA from 473 unaffected controls and 172 patients with sJIA was genotyped for a single nucleotide polymorphism (SNP) i ...[more]