Detecting transcriptionally active regions using genomic tiling arrays.
Ontology highlight
ABSTRACT:
SUBMITTER: Halasz G
PROVIDER: S-EPMC1779562 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Publications
Detecting transcriptionally active regions using genomic tiling arrays.
Halasz Gabor G van Batenburg Marinus F MF Perusse Joelle J Hua Sujun S Lu Xiang-Jun XJ White Kevin P KP Bussemaker Harmen J HJ
Genome biology 20060101 7
We have developed a method for interpreting genomic tiling array data, implemented as the program TranscriptionDetector. Probed loci expressed above background are identified by combining replicates in a way that makes minimal assumptions about the data. We performed medium-resolution Anopheles gambiae tiling array experiments and found extensive transcription of both coding and non-coding regions. Our method also showed improved detection of transcriptional units when applied to high-density ti ...[more]
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