Ontology highlight
ABSTRACT:
SUBMITTER: Kurochkin IV
PROVIDER: S-EPMC1794383 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Kurochkin Igor V IV Mizuno Yumi Y Konagaya Akihiko A Sakaki Yoshiyuki Y Schönbach Christian C Okazaki Yasushi Y
The EMBO journal 20070125 3
Peroxisomes play an important role in beta-oxidation of fatty acids. All peroxisomal matrix proteins are synthesized in the cytosol and post-translationally sorted to the organelle. Two distinct peroxisomal signal targeting sequences (PTSs), the C-terminal PTS1 and the N-terminal PTS2, have been defined. Import of precursor PTS2 proteins into the peroxisomes is accompanied by a proteolytic removal of the N-terminal targeting sequence. Although the PTS1 signal is preserved upon translocation, man ...[more]