Ontology highlight
ABSTRACT:
SUBMITTER: Lee SH
PROVIDER: S-EPMC1794506 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Lee Sang-Hoon SH Lee Yeon-Ah YA Woo Doo-Hyun DH Song Ran R Park Eun-Kyung EK Ryu Mi-Hyun MH Kim Young-Hoon YH Kim Kyoung-Soo KS Hong Seung-Jae SJ Yoo Myung Chul MC Yang Hyung-In HI
Arthritis research & therapy 20060101 6
The PD-1 (programmed death 1) molecule is a negative regulator of T cells. PDCD1 (programmed cell death 1) has been reported to have a genetic association in systemic lupus erythematosus and rheumatoid arthritis in Caucasians. However, there are no reports on the association between this gene and ankylosing spondylitis (AS). The present study investigated the association of the PD-1 polymorphisms and the haplotypes with AS in a Korean population sample. In a case-control association study, two s ...[more]