Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT.
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ABSTRACT:
SUBMITTER: Cheung TH
PROVIDER: S-EPMC1794569 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Publications
Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT.
Cheung Tom Hiu TH Kwan Yin Lam YL Hamady Micah M Liu Xuedong X
Genome biology 20061025 10
Deciphering gene regulatory networks requires the systematic identification of functional cis-acting regulatory elements. We present a suite of web-based bioinformatics tools, called GeneACT http://promoter.colorado.edu, that can rapidly detect evolutionarily conserved transcription factor binding sites or microRNA target sites that are either unique or over-represented in differentially expressed genes from DNA microarray data. GeneACT provides graphic visualization and extraction of common reg ...[more]
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