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Quantification of human bocavirus in lower respiratory tract infections in China.

ABSTRACT: A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 x 10(3) to 8.0 x 10(9) in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fever and cough. Our results suggest that HBoV may be an important etiological agent of LRTI in children in China.

SUBMITTER: Lin F

PROVIDER: S-EPMC1796861 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature

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Quantification of human bocavirus in lower respiratory tract infections in China.

Lin Feng F Zeng Aiping A Yang Ningmin N Lin Haiyan H Yang En E Wang Shengqi S Pintel David D Qiu Jianming J

Infectious agents and cancer 20070131

A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 x 10(3) to 8.0 x 10(9) in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fe ...[more]

PMID: 17266760

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