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RamB, the transcriptional regulator of acetate metabolism in Corynebacterium glutamicum, is subject to regulation by RamA and RamB.

ABSTRACT: In Corynebacterium glutamicum, the transcriptional regulator RamB negatively controls the expression of genes involved in acetate metabolism. Here we show that RamB represses its own expression by direct interaction with a 13-bp motif in the ramB promoter region. Additionally, ramB expression is subject to carbon source-dependent positive control by RamA.

SUBMITTER: Cramer A 

PROVIDER: S-EPMC1797322 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature

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RamB, the transcriptional regulator of acetate metabolism in Corynebacterium glutamicum, is subject to regulation by RamA and RamB.

Cramer Annette A   Auchter Marc M   Frunzke Julia J   Bott Michael M   Eikmanns Bernhard J BJ  

Journal of bacteriology 20061117 3

In Corynebacterium glutamicum, the transcriptional regulator RamB negatively controls the expression of genes involved in acetate metabolism. Here we show that RamB represses its own expression by direct interaction with a 13-bp motif in the ramB promoter region. Additionally, ramB expression is subject to carbon source-dependent positive control by RamA. ...[more]

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