Chronic Helicobacter pylori infection does not significantly alter the microbiota of the murine stomach.
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ABSTRACT:
SUBMITTER: Tan MP
PROVIDER: S-EPMC1800740 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
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Chronic Helicobacter pylori infection does not significantly alter the microbiota of the murine stomach.
Tan Mai Ping MP Kaparakis Maria M Galic Maja M Pedersen John J Pearse Martin M Wijburg Odilia L C OL Janssen Peter H PH Strugnell Richard A RA
Applied and environmental microbiology 20061201 3
We examined the impact of Helicobacter pylori infection on the murine gastric microbiota by culture and terminal-restriction fragment length polymorphism and found that neither acute nor chronic H. pylori infection substantially affected the gastric microbial composition. Interestingly, the total H. pylori burden detected by real-time PCR was significantly higher than that revealed by viable counts, suggesting that the antigenic load sustaining H. pylori-induced gastritis could be considerably h ...[more]
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