Ontology highlight
ABSTRACT:
SUBMITTER: Krajinovic M
PROVIDER: S-EPMC1801493 | biostudies-literature | 1995 Oct
REPOSITORIES: biostudies-literature
Krajinovic M M Pinamonti B B Sinagra G G Vatta M M Severini G M GM Milasin J J Falaschi A A Camerini F F Giacca M M Mestroni L L
American journal of human genetics 19951001 4
Idiopathic dilated cardiomyopathy is a heart muscle disease of unknown etiology, characterized by impaired myocardial contractility and ventricular dilatation. The disorder is an important cause of morbidity and mortality and represents the chief indication for heart transplantation. Familial transmission is often recognized (familial dilated cardiomyopathy, or FDC), mostly with autosomal dominant inheritance. In order to understand the molecular genetic basis of the disease, a large six-generat ...[more]