Ontology highlight
ABSTRACT:
SUBMITTER: Nemeth-Pongracz V
PROVIDER: S-EPMC1802613 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Németh-Pongrácz Veronika V Barabás Orsolya O Fuxreiter Mónika M Simon István I Pichová Iva I Rumlová Michalea M Zábranská Helena H Svergun Dmitri D Petoukhov Maxim M Harmat Veronika V Klement Eva E Hunyadi-Gulyás Eva E Medzihradszky Katalin F KF Kónya Emese E Vértessy Beáta G BG
Nucleic acids research 20061214 2
The homotrimeric fusion protein nucleocapsid (NC)-dUTPase combines domains that participate in RNA/DNA folding, reverse transcription, and DNA repair in Mason-Pfizer monkey betaretrovirus infected cells. The structural organization of the fusion protein remained obscured by the N- and C-terminal flexible segments of dUTPase and the linker region connecting the two domains that are invisible in electron density maps. Small-angle X-ray scattering reveals that upon oligonucleotide binding the NC do ...[more]