Ontology highlight
ABSTRACT:
SUBMITTER: Lawrence S
PROVIDER: S-EPMC1803772 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Journal of inflammation (London, England) 20070216
Neonatal monocytes display immaturity of numerous functions compared with adult cells. Gene expression arrays provide a promising tool for elucidating mechanisms underlying neonatal immune function. We used a well-established microarray to analyze differences between LPS-stimulated human cord blood and adult monocytes to create dynamic models for interactions to elucidate observed deficiencies in neonatal immune responses. We identified 168 genes that were differentially expressed between adult ...[more]