Ontology highlight
ABSTRACT:
SUBMITTER: Saad Y
PROVIDER: S-EPMC1808207 | biostudies-literature | 2007 Mar
REPOSITORIES: biostudies-literature
Saad Yasser Y Garrett Michael R MR Manickavasagam Ezhilarasi E Yerga-Woolwine Shane S Farms Phyllis P Radecki Tracy T Joe Bina B
Genomics 20070110 3
The presence of blood pressure (BP) quantitative trait loci (QTL) on rat chromosome 10 has been clearly demonstrated by linkage analysis and substitution mapping. Using congenic strains containing the LEW rat chromosomal segments on the Dahl salt-sensitive (S) rat background, further iterations of congenic substrains were constructed and characterized to fine-map a chromosome 10 region (QTL1) linked to blood pressure. Comparison of seven congenic substrains refined QTL1 to a 1.17 Mb segment flan ...[more]