The conversion of 3' UTRs into coding regions.
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ABSTRACT:
SUBMITTER: Giacomelli MG
PROVIDER: S-EPMC1808353 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Publications
The conversion of 3' UTRs into coding regions.
Giacomelli Michael G MG Hancock Adam S AS Masel Joanna J
Molecular biology and evolution 20061110 2
A possible origin of novel coding sequences is the removal of stop codons, leading to the inclusion of 3' untranslated regions (3' UTRs) within genes. We classified changes in the position of stop codons in closely related Saccharomyces species and in a mouse/rat comparison as either additions to or subtractions from coding regions. In both cases, the position of stop codons is highly labile, with more subtractions than additions found. The subtraction bias may be balanced by the input of new co ...[more]
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