Ontology highlight
ABSTRACT: Background
Settled dust has been used in studies to assess exposures to allergens and other biologically active components, but it has not been considered in the aggregate in relation to respiratory health outcomes in the general population.Objective
We addressed whether total house dust weight, an index of total dust exposure, was associated with respiratory health outcomes in the National Survey of Lead and Allergens in Housing (1998-1999) (NSLAH).Methods
NSLAH was a cross-sectional survey designed to represent permanently occupied housing units in the United States. In each household, a questionnaire was administered and settled dust was vacuumed from five locations. Linear regression models were used to identify predictors of dust weight; logistic regression models were used to examine the relationship between dust weight and asthma and wheeze.Results
Dust weight samples were available for 829 households, and survey information was available for 2,456 participants (children and adults). Lower income, older homes, household pets, having a smoker in the house, and less frequent cleaning predicted higher dust weight levels in U.S. households. Higher levels of dust weight were associated with greater odds of current asthma and wheeze. The strongest associations were seen for wheeze [adjusted odds ratio (OR) = 1.99; 95% confidence interval (CI), 1.21-3.28 for bedroom bed dust; OR = 2.81; 95% CI, 1.52-5.21 for upholstery dust). These associations persisted when adjusting for allergen and endotoxin exposures.Conclusions
Dust weight, an index of total dust exposure in the home, may contribute to respiratory outcomes independently of the exposure to specific components.
SUBMITTER: Elliott L
PROVIDER: S-EPMC1817708 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Elliott Leslie L Arbes Samuel J SJ Harvey Eric S ES Lee Robert C RC Salo Päivi M PM Cohn Richard D RD London Stephanie J SJ Zeldin Darryl C DC
Environmental health perspectives 20061107 2
<h4>Background</h4>Settled dust has been used in studies to assess exposures to allergens and other biologically active components, but it has not been considered in the aggregate in relation to respiratory health outcomes in the general population.<h4>Objective</h4>We addressed whether total house dust weight, an index of total dust exposure, was associated with respiratory health outcomes in the National Survey of Lead and Allergens in Housing (1998-1999) (NSLAH).<h4>Methods</h4>NSLAH was a cr ...[more]