Ontology highlight
ABSTRACT:
SUBMITTER: Pineda D
PROVIDER: S-EPMC18268 | biostudies-literature | 2000 Apr
REPOSITORIES: biostudies-literature
Pineda D D Gonzalez J J Callaerts P P Ikeo K K Gehring W J WJ Salo E E
Proceedings of the National Academy of Sciences of the United States of America 20000401 9
We have identified a sine oculis gene in the planarian Girardia tigrina (Platyhelminthes; Turbellaria; Tricladida). The planarian sine oculis gene (Gtso) encodes a protein with a sine oculis (Six) domain and a homeodomain that shares significant sequence similarity with so proteins assigned to the Six-2 gene family. Gtso is expressed as a single transcript in both regenerating and fully developed eyes. Whole-mount in situ hybridization studies show exclusive expression in photoreceptor cells. Lo ...[more]