Discovering potential pathogens among fungi identified as nonsporulating molds.
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ABSTRACT:
SUBMITTER: Pounder JI
PROVIDER: S-EPMC1829023 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Publications
Discovering potential pathogens among fungi identified as nonsporulating molds.
Pounder June I JI Simmon Keith E KE Barton Claudia A CA Hohmann Sheri L SL Brandt Mary E ME Petti Cathy A CA
Journal of clinical microbiology 20061129 2
Fungal infections are increasing, particularly among immunocompromised hosts, and a rapid diagnosis is essential to initiate antifungal therapy. Often fungi cannot be identified by conventional methods and are classified as nonsporulating molds (NSM). We sequenced internal transcribed spacer regions from 50 cultures of NSM and found 16 potential pathogens that can be associated with clinical disease. In selected clinical settings, identification of NSM could prove valuable and have an immediate ...[more]
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