Ontology highlight
ABSTRACT:
SUBMITTER: Pulukuri SM
PROVIDER: S-EPMC1832148 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Pulukuri Sai Murali Krishna SM Estes Norman N Patel Jitendra J Rao Jasti S JS
Cancer research 20070201 3
Increased expression of urokinase plasminogen activator (uPA) has been reported in various malignancies including prostate cancer. However, the mechanism by which uPA is abnormally expressed in prostate cancer remains elusive. Here, we show that uPA is aberrantly expressed in a high percentage of human prostate cancer tissues but rarely expressed either in tumor-matched nonneoplastic adjacent tissues or benign prostatic hyperplasia samples. This aberrant expression is associated with cancer-link ...[more]