Two small regulatory RNAs establish opposing fates of a developmental axis.
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ABSTRACT:
SUBMITTER: Nogueira FT
PROVIDER: S-EPMC1838527 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Publications
Two small regulatory RNAs establish opposing fates of a developmental axis.
Nogueira Fabio T S FT Madi Shahinez S Chitwood Daniel H DH Juarez Michelle T MT Timmermans Marja C P MC
Genes & development 20070401 7
Small RNAs are important regulators of gene expression. In maize, adaxial/abaxial (dorsoventral) leaf polarity is established by an abaxial gradient of microRNA166 (miR166), which spatially restricts the expression domain of class III homeodomain leucine zipper (HD-ZIPIII) transcription factors that specify adaxial/upper fate. Here, we show that leafbladeless1 encodes a key component in the trans-acting small interfering RNA (ta-siRNA) biogenesis pathway that acts on the adaxial side of developi ...[more]
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