Ontology highlight
ABSTRACT:
SUBMITTER: Meeson AP
PROVIDER: S-EPMC1847663 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Meeson Annette P AP Shi Xiaozhong X Alexander Matthew S MS Williams R S RS Allen Ronald E RE Jiang Nan N Adham Ibrahim M IM Goetsch Sean C SC Hammer Robert E RE Garry Daniel J DJ
The EMBO journal 20070315 7
The regulation of myogenic progenitor cells during muscle regeneration is not clearly understood. We have previously shown that the Foxk1 gene, a member of the forkhead/winged helix family of transcription factors, is expressed in myogenic progenitor cells in adult skeletal muscle. In the present study, we utilize transgenic technology and demonstrate that the 4.6 kb upstream fragment of the Foxk1 gene directs beta-galactosidase expression to the myogenic progenitor cell population. We further e ...[more]