Ontology highlight
ABSTRACT:
SUBMITTER: Friedrich NC
PROVIDER: S-EPMC1851037 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Friedrich Nancy C NC Torrents Eduard E Gibb Ewan A EA Sahlin Margareta M Sjöberg Britt-Marie BM Edgell David R DR
Proceedings of the National Academy of Sciences of the United States of America 20070329 15
In bacterial and phage genomes, coding regions are sometimes interrupted by self-splicing introns or inteins, which can encode mobility-promoting homing endonucleases. Homing endonuclease genes are also found free-standing (not intron- or intein-encoded) in phage genomes where they are inserted in intergenic regions. One example is the HNH family endonuclease, mobE, inserted between the large (nrdA) and small (nrdB) subunit genes of aerobic ribonucleotide reductase (RNR) of T-even phages T4, RB2 ...[more]