Ontology highlight
ABSTRACT:
SUBMITTER: Kannemeier C
PROVIDER: S-EPMC1851071 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Kannemeier Christian C Shibamiya Aya A Nakazawa Fumie F Trusheim Heidi H Ruppert Clemens C Markart Philipp P Song Yutong Y Tzima Eleni E Kennerknecht Elisabeth E Niepmann Michael M von Bruehl Marie-Luise ML Sedding Daniel D Massberg Steffen S Günther Andreas A Engelmann Bernd B Preissner Klaus T KT
Proceedings of the National Academy of Sciences of the United States of America 20070403 15
Upon vascular injury, locally controlled haemostasis prevents life-threatening blood loss and ensures wound healing. Intracellular material derived from damaged cells at these sites will become exposed to blood components and could contribute to blood coagulation and pathological thrombus formation. So far, the functional and mechanistic consequences of this concept are not understood. Here, we present in vivo and in vitro evidence that different forms of eukaryotic and prokaryotic RNA serve as ...[more]