Ontology highlight
ABSTRACT:
SUBMITTER: Robinson NP
PROVIDER: S-EPMC1851573 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Robinson Nicholas P NP Bell Stephen D SD
Proceedings of the National Academy of Sciences of the United States of America 20070328 14
In all three domains of life, DNA replication begins at specialized loci termed replication origins. In bacteria, replication initiates from a single, clearly defined site. In contrast, eukaryotic organisms exploit a multitude of replication origins, dividing their genomes into an array of short contiguous units. Recently, the multiple replication origin paradigm has also been demonstrated within the archaeal domain of life, with the discovery that the hyperthermophilic archaeon Sulfolobus has t ...[more]