Ontology highlight
ABSTRACT:
SUBMITTER: Hwang MG
PROVIDER: S-EPMC1851659 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Hwang Moo Gak MG Cho Myeon Haeng MH
Nucleic acids research 20070131 4
Telomeres are specific protein-DNA complexes that protect the ends of eukaryotic chromosomes from fusion and degradation and are maintained by a specialized mechanism exerted by telomerase and telomere-binding proteins (TBPs), which are evolutionarily conserved. AtTBP1 is an Arabidopsis thaliana protein that binds plant telomeric DNA in vitro. Here, we demonstrated that lack of AtTBP1 results in a deregulation of telomere length control, with mutant telomeres expanding steadily by the fourth gen ...[more]