Ontology highlight
ABSTRACT:
SUBMITTER: Lev-Maor G
PROVIDER: S-EPMC1852406 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Genome biology 20070101 2
<h4>Background</h4>Alu retroelements are specific to primates and abundant in the human genome. Through mutations that create functional splice sites within intronic Alus, these elements can become new exons in a process denoted exonization. It was recently shown that Alu elements are also heavily changed by RNA editing in the human genome.<h4>Results</h4>Here we show that the human nuclear prelamin A recognition factor contains a primate-specific Alu-exon that exclusively depends on RNA editing ...[more]