Ontology highlight
ABSTRACT:
SUBMITTER: Chae MS
PROVIDER: S-EPMC1855127 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Chae Michael S MS Lin Colin C CC Kessler Katherine E KE Nargang Cheryl E CE Tanton Lesley L LL Hahn Leanne B LB Nargang Frank E FE
Genetics 20070121 4
The nuclear aod-1 gene of Neurospora crassa encodes the alternative oxidase and is induced when the standard cytochrome-mediated respiratory chain of mitochondria is inhibited. To study elements of the pathway responsible for alternative oxidase induction, we generated a series of mutations in the region upstream from the aod-1 structural gene and transformed the constructs into an aod-1 mutant strain. Transformed conidia were plated on media containing antimycin A, which inhibits the cytochrome ...[more]