Ontology highlight
ABSTRACT:
SUBMITTER: Vivien E
PROVIDER: S-EPMC1855474 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20070112 4
The phytotoxin and polyketide antibiotic albicidin produced by Xanthomonas albilineans is a highly potent DNA gyrase inhibitor. Low yields of albicidin production have slowed studies of its chemical structure. Heterologous expression of albicidin biosynthetic genes in X. axonopodis pv. vesicatoria resulted in a sixfold increase in albicidin production, offering promising strategies for engineering overproduction. ...[more]