New mathematical modeling approach for predicting microbial inactivation by high hydrostatic pressure.

ABSTRACT: A new primary model based on a thermodynamically consistent first-order kinetic approach was constructed to describe non-log-linear inactivation kinetics of pressure-treated bacteria. The model assumes a first-order process in which the specific inactivation rate changes inversely with the square root of time. The model gave reasonable fits to experimental data over six to seven orders of magnitude. It was also tested on 138 published data sets and provided good fits in about 70% of cases in which the shape of the curve followed the typical convex upward form. In the remainder of published examples, curves contained additional shoulder regions or extended tail regions. Curves with shoulders could be accommodated by including an additional time delay parameter and curves with tails shoulder

SUBMITTER: Klotz B 

PROVIDER: S-EPMC1855581 | biostudies-literature | 2007 Apr

REPOSITORIES: biostudies-literature