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Children's vaccines do not induce cross reactivity against SARS-CoV.

ABSTRACT: In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.

SUBMITTER: Yu Y

PROVIDER: S-EPMC1860633 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature

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Children's vaccines do not induce cross reactivity against SARS-CoV.

Yu Yang Y Jin Huali H Chen Ze Z Yu Qingling L QL Ma Yijie J YJ Sun Xiaolin L XL Wang Bin B

Journal of clinical pathology 20070201 2

In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies th ...[more]

PMID: 17264247

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