Ontology highlight
ABSTRACT:
SUBMITTER: Bertin A
PROVIDER: S-EPMC1864844 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Biophysical journal 20070119 7
Using small-angle x-ray scattering, we probe the effect of histone tails on both internucleosomal interactions and nucleosome conformation. To get insight into the specific role of H3 and H4 histone tails, perfectly monodisperse recombinant nucleosome core particles were reconstituted, either intact or deprived of both H3 and H4 histone tails (gH3gH4). The main result is that H3 and H4 histone tails are necessary to induce attractive interactions between NCPs. A pair potential model was used to ...[more]