Ontology highlight
ABSTRACT:
SUBMITTER: Bubnick M
PROVIDER: S-EPMC1865664 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Bubnick Meggan M Smulian A George AG
Eukaryotic cell 20070223 4
Recombination events associated with sexual replication in pathogens may generate new strains with altered virulence. Histoplasma capsulatum is a mating-competent, pathogenic fungus with two described phenotypic mating types, + and -. The mating (MAT) locus of H. capsulatum was identified to facilitate molecular studies of mating in this organism. Through syntenic analysis of the H. capsulatum genomic sequence databases, a MAT1-1 idiomorph region was identified in H. capsulatum strains G217B and ...[more]