Ontology highlight
ABSTRACT:
SUBMITTER: Deng B
PROVIDER: S-EPMC1866054 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Journal of virology 20070110 7
Genetic and biochemical studies have suggested the existence of a bacteriophage-like, DNA-packaging/ejecting portal complex in herpesviruses capsids, but its arrangement remained unknown. Here, we report the first visualization of a unique vertex in the Kaposi's sarcoma-associated herpesvirus (KSHV) capsid by cryoelectron tomography, thus providing direct structural evidence for the existence of a portal complex in a gammaherpesvirus. This putative KSHV portal is an internally localized, umbilic ...[more]