Ontology highlight
ABSTRACT:
SUBMITTER: Sun X
PROVIDER: S-EPMC1866956 | biostudies-literature | 2006 Nov
REPOSITORIES: biostudies-literature
Sun Xingmin X Mierke Dale F DF Biswas Tapan T Lee Sang Yeol SY Landy Arthur A Radman-Livaja Marta M
Molecular cell 20061101 4
The highly directional and tightly regulated recombination reaction used to site-specifically excise the bacteriophage lambda chromosome out of its E. coli host chromosome requires the binding of six sequence-specific proteins to a 99 bp segment of the phage att site. To gain structural insights into this recombination pathway, we measured 27 FRET distances between eight points on the 99 bp regulatory DNA bound with all six proteins. Triangulation of these distances using a metric matrix distanc ...[more]